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Resource "KDN5" Version "1" (PlanDefinition)

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XML or JSON representation . provenance for this resource

National Comprehensive Cancer Network

Chemotherapy Order Template

Kidney Cancer

Gemcitabine/CARBOplatin

KDN5

INDICATION:

Metastatic or Relapsed – Collecting Duct/Medullary Subtypes

REFERENCES:

  1. NCCN Guidelines® for Kidney Cancer. V.3.2015.
  2. Oudard S, et al. J Urol. 2007;177(5):1698-702. a

NCCN SUPPORTIVE CARE:

  1. Emetic Risk:
    Day 1 Moderate
    Day 8 Low
  2. Fever Neutropenia Risk:
    Refer to NCCN Guidelines for Myeloid Growth Factors. V.2.2014

CHEMOTHERAPY REGIMEN

21-day cycle for 6 cycles

  • Gemcitabine 1250 mg/m2 IV over 30 minutes on Days 1 and 8
  • CARBOplatin AUC 5 IV over 30 minutes on Day 1

<?xml version="1.0" encoding="UTF-8"?>
<PlanDefinition xmlns="http://hl7.org/fhir">
  <id value="KDN5"/>
  <meta>
    <versionId value="1"/>
    <lastUpdated value="2018-09-20T01:09:26.644Z"/>
  </meta>
  <text>
    <status value="additional"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
      <table style="width: 100%">
        <tr>
          <td>
            <!--link to NCCN image-->
            <div style="width: 200px height: 100px vertical-align: top">National Comprehensive Cancer Network</div> </td>
          <td>
            <h3>Chemotherapy Order Template</h3>
            <h1>Kidney Cancer</h1>
            <h2>Gemcitabine/CARBOplatin</h2> </td>
          <td style="text-align: right vertical-align: top">KDN5</td> </tr> </table>
      <table style="width: 100% border-top: 1px solid border-bottom: 1px solid">
        <tr>
          <td style="width: 33% border-right: 1px solid vertical-align: top">
            <h4>INDICATION:</h4>
            <p>Metastatic or Relapsed &#8211; Collecting Duct/Medullary Subtypes</p> </td>
          <td style="width: 34% border-right: 1px solid vertical-align: top">
            <h4>REFERENCES:</h4>
            <ol>
              <li>
                <a href="http://www.example.org/professionals/physician_gls/PDF/kidney.pdf">NCCN Guidelines&#174; for Kidney Cancer. V.3.2015.</a>
              </li>
              <li>
                <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=%22The+Journal+of+urology%22%5BJour%5D+AND+1698%5Bpage%5D+AND+2007%5Bpdat%5D+AND+Oudard+S%5Bauthor%5D">Oudard S, et al.
                  <em>J Urol</em>. 2007177(5):1698-702.</a>
                <sup>
                  <a href="http://www.example.org/OrderTemplates/PDF/appendix_E.pdf">a</a>
                </sup> </li> </ol> </td>
          <td style="width: 33% vertical-align: top">
            <h4>NCCN SUPPORTIVE CARE:</h4>
            <ol>
              <li>
                <i>Emetic Risk:</i>
                <table>
                  <tr>
                    <td>Day 1</td>
                    <td>Moderate</td> </tr>
                  <tr>
                    <td>Day 8</td>
                    <td>Low</td> </tr> </table> </li>
              <li>
                <i>Fever Neutropenia Risk:</i>
                <br/>Refer to
                <a href="http://www.example.org/professionals/physician_gls/PDF/myeloid_growth.pdf">NCCN Guidelines for Myeloid Growth Factors. V.2.2014</a> </li> </ol> </td> </tr> </table>
      <!--same as the regimen section of the Composition resource only this version is without the style guide notes-->
      <h4>CHEMOTHERAPY REGIMEN</h4>
      <p>
        <i>21-day cycle for 6 cycles</i> </p>
      <ul>
        <li>Gemcitabine 1250 mg/m
          <sup>2</sup>IV over 30 minutes on Days 1 and 8</li>
        <li>CARBOplatin AUC 5 IV over 30 minutes on Day 1</li> </ul> </div>
  </text>
  <contained>
    <ActivityDefinition>
      <id value="1111"/>
      <status value="draft"/>
      <productCodeableConcept>
        <coding>
          <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
          <code value="12574"/>
          <display value="gemcitabine"/>
        </coding>
        <text value="gemcitabine"/>
      </productCodeableConcept>
      <dosage>
        <text value="1250 mg/m&#178; IV over 30 minutes"/>
        <timing>
          <repeat>
            <duration value="30"/>
            <durationUnit value="min"/>
          </repeat>
        </timing>
        <route>
          <text value="IV"/>
        </route>
        <doseQuantity>
          <value value="1250"/>
          <unit value="mg/m&#178;"/>
        </doseQuantity>
      </dosage>
    </ActivityDefinition>
  </contained>
  <contained>
    <ActivityDefinition>
      <id value="2222"/>
      <status value="draft"/>
      <productCodeableConcept>
        <coding>
          <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
          <code value="40048"/>
          <display value="Carboplatin"/>
        </coding>
        <text value="CARBOplatin"/>
      </productCodeableConcept>
      <dosage>
        <text value="AUC 5 IV over 30 minutes"/>
        <timing>
          <repeat>
            <duration value="30"/>
            <durationUnit value="min"/>
          </repeat>
        </timing>
        <route>
          <text value="IV"/>
        </route>
        <doseQuantity>
          <extension url="http://example.org/fhir/AUC-dose">
            <valueInteger value="5"/>
          </extension>
        </doseQuantity>
      </dosage>
    </ActivityDefinition>
  </contained>
  <identifier>
    <system value="http://example.org/ordertemplates"/>
    <value value="KDN5"/>
  </identifier>
  <version value="1"/>
  <title value="Gemcitabine/CARBOplatin"/>
  <type>
    <text value="Chemotherapy Order Template"/>
  </type>
  <status value="draft"/>
  <experimental value="true"/>
  <publisher value="National Comprehensive Cancer Network, Inc."/>
  <approvalDate value="2016-07-27"/>
  <lastReviewDate value="2016-07-27"/>
  <useContext>
    <extension url="http://hl7.org/fhir/StructureDefinition/usagecontext-group">
      <valueString value="A"/>
    </extension>
    <code>
      <system value="http://example.org/fhir/CodeSystem/indications"/>
      <code value="treamentSetting-or-diseaseStatus"/>
    </code>
    <valueCodeableConcept>
      <text value="Metastatic"/>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <extension url="http://hl7.org/fhir/StructureDefinition/usagecontext-group">
      <valueString value="A"/>
    </extension>
    <code>
      <system value="http://example.org/fhir/CodeSystem/indications"/>
      <code value="disease-or-histology"/>
    </code>
    <valueCodeableConcept>
      <text value="Collecting Duct/Medullary Subtypes"/>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <extension url="http://hl7.org/fhir/StructureDefinition/usagecontext-group">
      <valueString value="A"/>
    </extension>
    <code>
      <system value="http://hl7.org/fhir/usage-context-type"/>
      <code value="focus"/>
    </code>
    <valueCodeableConcept>
      <text value="Kidney Cancer"/>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <extension url="http://hl7.org/fhir/StructureDefinition/usagecontext-group">
      <valueString value="B"/>
    </extension>
    <code>
      <system value="http://example.org/fhir/CodeSystem/indications"/>
      <code value="treatmentSetting-or-diseaseStatus"/>
    </code>
    <valueCodeableConcept>
      <text value="Relapsed"/>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <extension url="http://hl7.org/fhir/StructureDefinition/usagecontext-group">
      <valueString value="B"/>
    </extension>
    <code>
      <system value="http://example.org/fhir/CodeSystem/indications"/>
      <code value="disease-or-histology"/>
    </code>
    <valueCodeableConcept>
      <text value="Collecting Duct/Medullary Subtypes"/>
    </valueCodeableConcept>
  </useContext>
  <useContext>
    <extension url="http://hl7.org/fhir/StructureDefinition/usagecontext-group">
      <valueString value="B"/>
    </extension>
    <code>
      <system value="http://hl7.org/fhir/usage-context-type"/>
      <code value="focus"/>
    </code>
    <valueCodeableConcept>
      <text value="Kidney Cancer &#8211; Collecting Duct/Medullary Subtypes - Metastatic"/>
    </valueCodeableConcept>
  </useContext>
  <contributor>
    <type value="author"/>
    <name value="Lee Surprenant"/>
  </contributor>
  <copyright value="All rights reserved."/>
  <relatedArtifact>
    <type value="derived-from"/>
    <display value="NCCN Guidelines for Kidney Cancer. V.2.2016"/>
    <url value="http://www.example.org/professionals/physician_gls/PDF/kidney.pdf"/>
  </relatedArtifact>
  <relatedArtifact>
    <type value="citation">
      <extension url="http://example.org/fhir/regimenReferenceType">
        <valueCode value="a"/>
      </extension>
    </type>
    <citation value="Oudard S, et al. J Urol. 2007177(5):1698-702"/>
    <url value="http://www.ncbi.nlm.nih.gov/pubmed/17437788"/>
  </relatedArtifact>
  <action>
    <selectionBehavior value="exactly-one"/>
    <action>
      <selectionBehavior value="all"/>
      <action>
        <groupingBehavior value="sentence-group"/>
        <selectionBehavior value="exactly-one"/>
        <action id="cycle-definition-1">
          <textEquivalent value="21-day cycle for 6 cycles"/>
          <timingTiming>
            <repeat>
              <count value="6"/>
              <duration value="21"/>
              <durationUnit value="d"/>
            </repeat>
          </timingTiming>
          <action id="action-1">
            <extension url="http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle">
              <extension url="day">
                <valueInteger value="1"/>
              </extension>
              <extension url="day">
                <valueInteger value="8"/>
              </extension>
            </extension>
            <textEquivalent value="Gemcitabine 1250 mg/m&#178; IV over 30 minutes on days 1 and 8"/>
            <definition>
              <reference value="#1111"/>
            </definition>
          </action>
          <action id="action-2">
            <extension url="http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle">
              <extension url="day">
                <valueInteger value="1"/>
              </extension>
            </extension>
            <textEquivalent value="CARBOplatin AUC 5 IV over 30 minutes on Day 1"/>
            <relatedAction>
              <actionId value="action-1"/>
              <relationship value="concurrent-with-start"/>
            </relatedAction>
            <definition>
              <reference value="#2222"/>
            </definition>
          </action>
        </action>
      </action>
    </action>
  </action>
</PlanDefinition>