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Resource "ResearchStudy" Version "1" (StructureDefinition)

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XML or JSON representation. Try out the Profile as a questionnaire based web form . Edit this as XML or JSON. provenance for this resource

Name Flags Card. Type Description & Constraints doco
. . ResearchStudy TU DomainResource Investigation to increase healthcare-related patient-independent knowledge
Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension
. . . identifier Σ 0..* Identifier Business Identifier for study
. . . title Σ 0..1 string Name for this study
. . . protocol Σ 0..* Reference( PlanDefinition) Steps followed in executing study
. . . partOf Σ 0..* Reference( ResearchStudy) Part of larger study
. . . status ?! Σ 1..1 code active | administratively-completed | approved | closed-to-accrual | closed-to-accrual-and-intervention | completed | disapproved | in-review | temporarily-closed-to-accrual | temporarily-closed-to-accrual-and-intervention | withdrawn
ResearchStudyStatus ( Required)
. . . primaryPurposeType Σ 0..1 CodeableConcept treatment | prevention | diagnostic | supportive-care | screening | health-services-research | basic-science | device-feasibility
ResearchStudyPrimaryPurposeType ( Extensible)
. . . phase Σ 0..1 CodeableConcept n-a | early-phase-1 | phase-1 | phase-1-phase-2 | phase-2 | phase-2-phase-3 | phase-3 | phase-4
ResearchStudyPhase ( Example)
. . . category Σ 0..* CodeableConcept Classifications for the study
. . . focus Σ 0..* CodeableConcept Drugs, devices, etc. under study
. . . condition Σ 0..* CodeableConcept Condition being studied
Condition/Problem/Diagnosis Codes ( Example)
. . . contact Σ 0..* ContactDetail Contact details for the study
. . . relatedArtifact 0..* RelatedArtifact References and dependencies
. . . keyword Σ 0..* CodeableConcept Used to search for the study
. . . location Σ 0..* CodeableConcept Geographic region(s) for study
Jurisdiction ( Extensible)
. . . description 0..1 markdown What this is study doing
. . . enrollment Σ 0..* Reference( Group) Inclusion & exclusion criteria
. . . period Σ 0..1 Period When the study began and ended
. . . sponsor Σ 0..1 Reference( Organization) Organization that initiates and is legally responsible for the study
. . . principalInvestigator Σ 0..1 Reference( Practitioner | PractitionerRole) Researcher who oversees multiple aspects of the study
. . . site Σ 0..* Reference( Location) Facility where study activities are conducted
. . . reasonStopped Σ 0..1 CodeableConcept accrual-goal-met | closed-due-to-toxicity | closed-due-to-lack-of-study-progress | temporarily-closed-per-study-design
ResearchStudyReasonStopped ( Example)
. . . note 0..* Annotation Comments made about the study
. . . arm 0..* BackboneElement Defined path through the study for a subject
. . . . name 1..1 string Label for study arm
. . . . type 0..1 CodeableConcept Categorization of study arm
. . . . description 0..1 string Short explanation of study path
. . . objective 0..* BackboneElement A goal for the study
. . . . name 0..1 string Label for the objective
. . . . type 0..1 CodeableConcept primary | secondary | exploratory
ResearchStudyObjectiveType ( Preferred)

doco Documentation for this format

{
  "resourceType" : "StructureDefinition",
  "id" : "ResearchStudy",
  "meta" : {
    "versionId" : "1",
    "lastUpdated" : "2018-12-14T02:04:34.176Z"
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n <table style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\">\n <tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\">\n <th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a title=\"The logical name of the element\" href=\"formats.html#table\">Name</a>\n </th>\n <th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a title=\"Information about the use of the element\" href=\"formats.html#table\">Flags</a>\n </th>\n <th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a title=\"Minimum and Maximum # of times the the element can appear in the instance\" href=\"formats.html#table\">Card.</a>\n </th>\n <th style=\"width: 100px\" class=\"hierarchy\">\n <a title=\"Reference to the type of the element\" href=\"formats.html#table\">Type</a>\n </th>\n <th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a title=\"Additional information about the element\" href=\"formats.html#table\">Description &amp; Constraints</a>\n <span style=\"float: right\">\n <a title=\"Legend for this format\" href=\"formats.html#table\">\n <img alt=\"doco\" style=\"background-color: inherit\"/>\n </a>\n </span>\n </th>\n </tr>\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAACCElEQVQ4y4XTv2sUQRTA8e9Mzt3kjoOLSXFgZ6GJQlALCysLC89OsLTXv0VFxE4stRAEQUghSWEXuM4qMZpATsUD70dyMdnduZ15z2IvMV5IfDDNm5nPm59GVTkpms1mTVXvhxDuichlEZn03m+KyJL3/mWj0fiKqp7YVlZWXrfbbR2PTqeji4uLn1WVEqdECKFRr9eP5WdnZ/HeXwROB0TEA3S7XarVKiLC1tYW8/PzeO/5LxBCUABrLXEc02q1KJfLB30F0P144dPU9LVL1kwcrU06WP0ewhML4JwDYDgcHo7I87wAjNq5ypU3Z8arT8F5u/xejw52zmGM+Rcg1wyIcc/BTYCdBlODyh3ElA1AHMekaUoURURRBECWZSNgaGzBxxAU9jfQ9jrJr2dcbbXobRYHlQAzo9X1gDR9+KUArE6CwLefZD9WCW6P0uRZKreXqADkHXZ3dshzjwRholJH397AOXcTwHTfzQ1n7q6NnYEAy+DWQVNwKWQJ6vcx557Se7HAzIN1M9rCwVteA/rAYDRRICQgSZEr7WLYO3bzJVJGQBu0D74PkoHkoBnIHvjfkO9AGABmDHCjFWgH8i7kPQh9yEeYH4DfLhBJgA2A7BBQJ9uwXWY3rhJqFo1AaiB1CBngwKZQcqAeSFSduL9Akj7qPF64jnALS5VTPwdgPwwJ+uog9Qcx4kRZiPKqxgAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Resource\"/> \n <span title=\"ResearchStudy : A process where a researcher or organization plans and then executes a series of steps intended to increase the field of healthcare-related knowledge. This includes studies of safety, efficacy, comparative effectiveness and other information about medications, devices, therapies and other interventional and investigative techniques. A ResearchStudy involves the gathering of information about human or animal subjects.\">ResearchStudy</span>\n <a name=\"ResearchStudy\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold; color: black; background-color: #fff5e6\" href=\"versions.html#std-process\" title=\"Standards Status = Trial Use\">TU</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"domainresource.html\">DomainResource</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Investigation to increase healthcare-related patient-independent knowledge\n <br/>Elements defined in Ancestors: \n <a title=\"The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.\" href=\"resource.html#Resource\">id</a>, \n <a title=\"The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.\" href=\"resource.html#Resource\">meta</a>, \n <a title=\"A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.\" href=\"resource.html#Resource\">implicitRules</a>, \n <a title=\"The base language in which the resource is written.\" href=\"resource.html#Resource\">language</a>, \n <a title=\"A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.\" href=\"domainresource.html#DomainResource\">text</a>, \n <a title=\"These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.\" href=\"domainresource.html#DomainResource\">contained</a>, \n <a title=\"May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.\" href=\"domainresource.html#DomainResource\">extension</a>, \n <a title=\"May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element&apos;s descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.&#10;&#10;Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).\" href=\"domainresource.html#DomainResource\">modifierExtension</a>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.identifier : Identifiers assigned to this research study by the sponsor or other systems.\">identifier</span>\n <a name=\"ResearchStudy.identifier\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#Identifier\">Identifier</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Business Identifier for study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\"/> \n <span title=\"ResearchStudy.title : A short, descriptive user-friendly label for the study.\">title</span>\n <a name=\"ResearchStudy.title\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#string\">string</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Name for this study</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\"/> \n <span title=\"ResearchStudy.protocol : The set of steps expected to be performed as part of the execution of the study.\">protocol</span>\n <a name=\"ResearchStudy.protocol\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"references.html#Reference\">Reference</a>(\n <a href=\"plandefinition.html\">PlanDefinition</a>)\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Steps followed in executing study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\"/> \n <span title=\"ResearchStudy.partOf : A larger research study of which this particular study is a component or step.\">partOf</span>\n <a name=\"ResearchStudy.partOf\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"references.html#Reference\">Reference</a>(\n <a href=\"researchstudy.html\">ResearchStudy</a>)\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Part of larger study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\"/> \n <span title=\"ResearchStudy.status : The current state of the study.\">status</span>\n <a name=\"ResearchStudy.status\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"conformance-rules.html#isModifier\" title=\"This element is a modifier element\">?!</a>\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#code\">code</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">active | administratively-completed | approved | closed-to-accrual | closed-to-accrual-and-intervention | completed | disapproved | in-review | temporarily-closed-to-accrual | temporarily-closed-to-accrual-and-intervention | withdrawn\n <br/>\n <a title=\"Codes that convey the current status of the research study.\" href=\"valueset-research-study-status.html\">ResearchStudyStatus</a> (\n <a title=\"To be conformant, the concept in this element SHALL be from the specified value set.\" href=\"terminologies.html#required\">Required</a>)\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.primaryPurposeType : The type of study based upon the intent of the study&apos;s activities. A classification of the intent of the study.\">primaryPurposeType</span>\n <a name=\"ResearchStudy.primaryPurposeType\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">treatment | prevention | diagnostic | supportive-care | screening | health-services-research | basic-science | device-feasibility\n <br/>\n <a title=\"Codes for the main intent of the study.\" href=\"valueset-research-study-prim-purp-type.html\">ResearchStudyPrimaryPurposeType</a> (\n <a title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" href=\"terminologies.html#extensible\">Extensible</a>)\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.phase : The stage in the progression of a therapy from initial experimental use in humans in clinical trials to post-market evaluation.\">phase</span>\n <a name=\"ResearchStudy.phase\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">n-a | early-phase-1 | phase-1 | phase-1-phase-2 | phase-2 | phase-2-phase-3 | phase-3 | phase-4\n <br/>\n <a title=\"Codes for the stage in the progression of a therapy from initial experimental use in humans in clinical trials to post-market evaluation.\" href=\"valueset-research-study-phase.html\">ResearchStudyPhase</a> (\n <a title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\" href=\"terminologies.html#example\">Example</a>)\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.category : Codes categorizing the type of study such as investigational vs. observational, type of blinding, type of randomization, safety vs. efficacy, etc.\">category</span>\n <a name=\"ResearchStudy.category\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Classifications for the study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.focus : The medication(s), food(s), therapy(ies), device(s) or other concerns or interventions that the study is seeking to gain more information about.\">focus</span>\n <a name=\"ResearchStudy.focus\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Drugs, devices, etc. under study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.condition : The condition that is the focus of the study. For example, In a study to examine risk factors for Lupus, might have as an inclusion criterion &quot;healthy volunteer&quot;, but the target condition code would be a Lupus SNOMED code.\">condition</span>\n <a name=\"ResearchStudy.condition\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Condition being studied\n <br/>\n <a title=\"Identification of the condition or diagnosis.\" href=\"valueset-condition-code.html\">Condition/Problem/Diagnosis Codes</a> (\n <a title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\" href=\"terminologies.html#example\">Example</a>)\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.contact : Contact details to assist a user in learning more about or engaging with the study.\">contact</span>\n <a name=\"ResearchStudy.contact\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"metadatatypes.html#ContactDetail\">ContactDetail</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Contact details for the study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.relatedArtifact : Citations, references and other related documents.\">relatedArtifact</span>\n <a name=\"ResearchStudy.relatedArtifact\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"metadatatypes.html#RelatedArtifact\">RelatedArtifact</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">References and dependencies\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.keyword : Key terms to aid in searching for or filtering the study.\">keyword</span>\n <a name=\"ResearchStudy.keyword\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Used to search for the study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.location : Indicates a country, state or other region where the study is taking place.\">location</span>\n <a name=\"ResearchStudy.location\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Geographic region(s) for study\n <br/>\n <a title=\"Countries and regions within which this artifact is targeted for use.\" href=\"valueset-jurisdiction.html\">Jurisdiction</a> (\n <a title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated. If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\" href=\"terminologies.html#extensible\">Extensible</a>)\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\"/> \n <span title=\"ResearchStudy.description : A full description of how the study is being conducted.\">description</span>\n <a name=\"ResearchStudy.description\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#markdown\">markdown</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">What this is study doing</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\"/> \n <span title=\"ResearchStudy.enrollment : Reference to a Group that defines the criteria for and quantity of subjects participating in the study. E.g. &quot; 200 female Europeans between the ages of 20 and 45 with early onset diabetes&quot;.\">enrollment</span>\n <a name=\"ResearchStudy.enrollment\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"references.html#Reference\">Reference</a>(\n <a href=\"group.html\">Group</a>)\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Inclusion &amp; exclusion criteria\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.period : Identifies the start date and the expected (or actual, depending on status) end date for the study.\">period</span>\n <a name=\"ResearchStudy.period\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#Period\">Period</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">When the study began and ended</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\"/> \n <span title=\"ResearchStudy.sponsor : An organization that initiates the investigation and is legally responsible for the study.\">sponsor</span>\n <a name=\"ResearchStudy.sponsor\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"references.html#Reference\">Reference</a>(\n <a href=\"organization.html\">Organization</a>)\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Organization that initiates and is legally responsible for the study</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\"/> \n <span title=\"ResearchStudy.principalInvestigator : A researcher in a study who oversees multiple aspects of the study, such as concept development, protocol writing, protocol submission for IRB approval, participant recruitment, informed consent, data collection, analysis, interpretation and presentation.\">principalInvestigator</span>\n <a name=\"ResearchStudy.principalInvestigator\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"references.html#Reference\">Reference</a>(\n <a href=\"practitioner.html\">Practitioner</a> | \n <a href=\"practitionerrole.html\">PractitionerRole</a>)\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Researcher who oversees multiple aspects of the study</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Reference to another Resource\"/> \n <span title=\"ResearchStudy.site : A facility in which study activities are conducted.\">site</span>\n <a name=\"ResearchStudy.site\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"references.html#Reference\">Reference</a>(\n <a href=\"location.html\">Location</a>)\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Facility where study activities are conducted\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.reasonStopped : A description and/or code explaining the premature termination of the study.\">reasonStopped</span>\n <a name=\"ResearchStudy.reasonStopped\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a style=\"padding-left: 3px; padding-right: 3px; color: black; background-color: white\" href=\"elementdefinition-definitions.html#ElementDefinition.isSummary\" title=\"This element is included in summaries\">&#931;</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">accrual-goal-met | closed-due-to-toxicity | closed-due-to-lack-of-study-progress | temporarily-closed-per-study-design\n <br/>\n <a title=\"Codes for why the study ended prematurely.\" href=\"valueset-research-study-reason-stopped.html\">ResearchStudyReasonStopped</a> (\n <a title=\"Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included.\" href=\"terminologies.html#example\">Example</a>)\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.note : Comments made about the study by the performer, subject or other participants.\">note</span>\n <a name=\"ResearchStudy.note\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#Annotation\">Annotation</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Comments made about the study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\"/> \n <span title=\"ResearchStudy.arm : Describes an expected sequence of events for one of the participants of a study. E.g. Exposure to drug A, wash-out, exposure to drug B, wash-out, follow-up.\">arm</span>\n <a name=\"ResearchStudy.arm\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"backboneelement.html\">BackboneElement</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Defined path through the study for a subject\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\"/> \n <span title=\"ResearchStudy.arm.name : Unique, human-readable label for this arm of the study.\">name</span>\n <a name=\"ResearchStudy.arm.name\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#string\">string</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Label for study arm</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.arm.type : Categorization of study arm, e.g. experimental, active comparator, placebo comparater.\">type</span>\n <a name=\"ResearchStudy.arm.type\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Categorization of study arm</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\"/> \n <span title=\"ResearchStudy.arm.description : A succinct description of the path through the study that would be followed by a subject adhering to this arm.\">description</span>\n <a name=\"ResearchStudy.arm.description\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#string\">string</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Short explanation of study path</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,R0lGODlhEAAQAPQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///wD/ACH5BAEKAB8ALAAAAAAQABAAAAVl4CeOZGme5qCqqDg8jyVJaz1876DsmAQAgqDgltspMEhMJoMZ4iy6I1AooFCIv+wKybziALVAoAEjYLwDgGIpJhMslgxaLR4/3rMAWoBp32V5exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\"/> \n <span title=\"ResearchStudy.objective : A goal that the study is aiming to achieve in terms of a scientific question to be answered by the analysis of data collected during the study.\">objective</span>\n <a name=\"ResearchStudy.objective\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"backboneelement.html\">BackboneElement</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A goal for the study\n <br/>\n </td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAALElEQVR42u3QwQkAMAwDsezq/WdIO4XJQwa9DTdJpulv258AAMANIgAAADUPYAVAgAJ//usAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARklEQVQ4y2P8//8/AyWAhYFCMAgMuHjx4n+KXaCv+I0szW8WpCG8kFO1lGFKW/SIjAUYgxz/MzAwMDC+nqhDUTQyjuYFBgCNmhP4OvTRgwAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\"/> \n <span title=\"ResearchStudy.objective.name : Unique, human-readable label for this objective of the study.\">name</span>\n <a name=\"ResearchStudy.objective.name\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#string\">string</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Label for the objective</td>\n </tr>\n\n <tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;\">\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAAAASUVORK5CYII=)\" class=\"hierarchy\">\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiYFCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC\" class=\"hierarchy\" alt=\".\" style=\"background-color: inherit\"/>\n <img src=\"data: image/png;base64,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\" class=\"hierarchy\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\"/> \n <span title=\"ResearchStudy.objective.type : The kind of study objective.\">type</span>\n <a name=\"ResearchStudy.objective.type\"> </a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">\n <a href=\"datatypes.html#CodeableConcept\">CodeableConcept</a>\n </td>\n <td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">primary | secondary | exploratory\n <br/>\n <a title=\"Codes for the kind of study objective.\" href=\"valueset-research-study-objective-type.html\">ResearchStudyObjectiveType</a> (\n <a title=\"Instances are encouraged to draw from the specified codes for interoperability purposes but are not required to do so to be considered conformant.\" href=\"terminologies.html#preferred\">Preferred</a>)\n </td>\n </tr>\n\n <tr>\n <td colspan=\"5\" class=\"hierarchy\">\n <br/>\n <a title=\"Legend for this format\" href=\"formats.html#table\">\n <img alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format\n </a>\n </td>\n </tr>\n </table>\n </div>"
  },
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode" : "trial-use"
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger" : 0
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category",
      "valueCode" : "business"
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode" : "brr"
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-category",
      "valueString" : "Specialized.Public Health &amp; Research"
    }
  ],
  "url" : "http://hl7.org/fhir/StructureDefinition/ResearchStudy",
  "version" : "4.0.0",
  "name" : "ResearchStudy",
  "status" : "draft",
  "date" : "2018-12-14T01:14:32+00:00",
  "publisher" : "Health Level Seven International (Biomedical Research and Regulation)",
  "contact" : [
    {
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://hl7.org/fhir"
        }
      ]
    },
    {
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://www.hl7.org/Special/committees/rcrim/index.cfm"
        }
      ]
    }
  ],
  "description" : "A process where a researcher or organization plans and then executes a series of steps intended to increase the field of healthcare-related knowledge. This includes studies of safety, efficacy, comparative effectiveness and other information about medications, devices, therapies and other interventional and investigative techniques. A ResearchStudy involves the gathering of information about human or animal subjects.",
  "fhirVersion" : "4.0.0",
  "mapping" : [
    {
      "identity" : "BRIDG5.1",
      "uri" : "https://bridgmodel.nci.nih.gov",
      "name" : "BRIDG 5.1 Mapping"
    },
    {
      "identity" : "v2",
      "uri" : "http://hl7.org/v2",
      "name" : "HL7 v2 Mapping"
    },
    {
      "identity" : "rim",
      "uri" : "http://hl7.org/v3",
      "name" : "RIM Mapping"
    },
    {
      "identity" : "clinicaltrials-gov",
      "uri" : "http://clinicaltrials.gov",
      "name" : "ClinicalTrials.gov Mapping"
    },
    {
      "identity" : "w5",
      "uri" : "http://hl7.org/fhir/fivews",
      "name" : "FiveWs Pattern Mapping"
    }
  ],
  "kind" : "resource",
  "abstract" : false,
  "type" : "ResearchStudy",
  "baseDefinition" : "http://hl7.org/fhir/StructureDefinition/DomainResource",
  "derivation" : "specialization",
  "snapshot" : {
    "element" : [
      {
        "id" : "ResearchStudy",
        "path" : "ResearchStudy",
        "short" : "Investigation to increase healthcare-related patient-independent knowledge",
        "definition" : "A process where a researcher or organization plans and then executes a series of steps intended to increase the field of healthcare-related knowledge. This includes studies of safety, efficacy, comparative effectiveness and other information about medications, devices, therapies and other interventional and investigative techniques. A ResearchStudy involves the gathering of information about human or animal subjects.",
        "comment" : "Need to make sure we encompass public health studies.",
        "alias" : [
          "Clinical Trial",
          "Study"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy",
          "min" : 0,
          "max" : "*"
        },
        "constraint" : [
          {
            "key" : "dom-2",
            "severity" : "error",
            "human" : "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
            "expression" : "contained.contained.empty()",
            "xpath" : "not(parent::f:contained and f:contained)",
            "source" : "DomainResource"
          },
          {
            "key" : "dom-4",
            "severity" : "error",
            "human" : "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
            "expression" : "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
            "xpath" : "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
            "source" : "DomainResource"
          },
          {
            "key" : "dom-3",
            "severity" : "error",
            "human" : "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
            "expression" : "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
            "xpath" : "not(exists(for $contained in f:contained return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
            "source" : "DomainResource"
          },
          {
            "extension" : [
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
                "valueBoolean" : true
              },
              {
                "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
                "valueMarkdown" : "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
              }
            ],
            "key" : "dom-6",
            "severity" : "warning",
            "human" : "A resource should have narrative for robust management",
            "expression" : "text.div.exists()",
            "xpath" : "exists(f:text/h:div)",
            "source" : "DomainResource"
          },
          {
            "key" : "dom-5",
            "severity" : "error",
            "human" : "If a resource is contained in another resource, it SHALL NOT have a security label",
            "expression" : "contained.meta.security.empty()",
            "xpath" : "not(exists(f:contained/*/f:meta/f:security))",
            "source" : "DomainResource"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "Entity. Role, or Act"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "ObservationalStudyProtocolVersion; Study;\nStudyProtocolVersion"
          },
          {
            "identity" : "v2",
            "map" : "OBX"
          },
          {
            "identity" : "rim",
            "map" : "Observation[classCode=CLNTRL, moodCode=EVN]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.id",
        "path" : "ResearchStudy.id",
        "short" : "Logical id of this artifact",
        "definition" : "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
        "comment" : "The only time that a resource does not have an id is when it is being submitted to the server using a create operation.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Resource.id",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "id"
          }
        ],
        "isModifier" : false,
        "isSummary" : true
      },
      {
        "id" : "ResearchStudy.meta",
        "path" : "ResearchStudy.meta",
        "short" : "Metadata about the resource",
        "definition" : "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Resource.meta",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "Meta"
          }
        ],
        "isModifier" : false,
        "isSummary" : true
      },
      {
        "id" : "ResearchStudy.implicitRules",
        "path" : "ResearchStudy.implicitRules",
        "short" : "A set of rules under which this content was created",
        "definition" : "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
        "comment" : "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Resource.implicitRules",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "uri"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
        "isSummary" : true
      },
      {
        "id" : "ResearchStudy.language",
        "path" : "ResearchStudy.language",
        "short" : "Language of the resource content",
        "definition" : "The base language in which the resource is written.",
        "comment" : "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Resource.language",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "code"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
              "valueCanonical" : "http://hl7.org/fhir/ValueSet/all-languages"
            },
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "Language"
            },
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean" : true
            }
          ],
          "strength" : "preferred",
          "description" : "A human language.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/languages"
        }
      },
      {
        "id" : "ResearchStudy.text",
        "path" : "ResearchStudy.text",
        "short" : "Text summary of the resource, for human interpretation",
        "definition" : "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
        "comment" : "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
        "alias" : [
          "narrative",
          "html",
          "xhtml",
          "display"
        ],
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "DomainResource.text",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "Narrative"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "Act.text?"
          }
        ]
      },
      {
        "id" : "ResearchStudy.contained",
        "path" : "ResearchStudy.contained",
        "short" : "Contained, inline Resources",
        "definition" : "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.",
        "comment" : "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
        "alias" : [
          "inline resources",
          "anonymous resources",
          "contained resources"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "DomainResource.contained",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Resource"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "ResearchStudy.extension",
        "path" : "ResearchStudy.extension",
        "short" : "Additional content defined by implementations",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias" : [
          "extensions",
          "user content"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "DomainResource.extension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "ResearchStudy.modifierExtension",
        "path" : "ResearchStudy.modifierExtension",
        "short" : "Extensions that cannot be ignored",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias" : [
          "extensions",
          "user content"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "DomainResource.modifierExtension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "ResearchStudy.identifier",
        "path" : "ResearchStudy.identifier",
        "short" : "Business Identifier for study",
        "definition" : "Identifiers assigned to this research study by the sponsor or other systems.",
        "requirements" : "Allows identification of the research study as it is known by various participating systems and in a way that remains consistent across servers.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.identifier",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Identifier"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Organization's Unique Protocol ID; Secondary IDs"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.identifier"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping (although there is DocumentVersion.identifier > StudyProtocolDocumentVersion, this is arguably a different semantic)"
          },
          {
            "identity" : "rim",
            "map" : ".identifier"
          }
        ]
      },
      {
        "id" : "ResearchStudy.title",
        "path" : "ResearchStudy.title",
        "short" : "Name for this study",
        "definition" : "A short, descriptive user-friendly label for the study.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.title",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "string"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Brief Title"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping (although there is StudyProtocolDocumentVersionPublicTitle this is arguably a different semantic: title of a document vs title of a research study)"
          }
        ]
      },
      {
        "id" : "ResearchStudy.protocol",
        "path" : "ResearchStudy.protocol",
        "short" : "Steps followed in executing study",
        "definition" : "The set of steps expected to be performed as part of the execution of the study.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.protocol",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/PlanDefinition"
            ]
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Interventions; Arm/Intervention Cross-Reference"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolDocumentVersionPublicTitle.name"
          },
          {
            "identity" : "rim",
            "map" : ".outboundRelationship[typeCode=DEFN].target"
          }
        ]
      },
      {
        "id" : "ResearchStudy.partOf",
        "path" : "ResearchStudy.partOf",
        "short" : "Part of larger study",
        "definition" : "A larger research study of which this particular study is a component or step.",
        "requirements" : "Allows breaking a study into components (e.g. by study site) each with their own PI, status, enrollment, etc.",
        "alias" : [
          "container"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.partOf",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/ResearchStudy"
            ]
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "CompanionStudyRelationship"
          },
          {
            "identity" : "rim",
            "map" : ".inboundRelationship[typeCode=COMP].source[moodCode=EVN]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.status",
        "path" : "ResearchStudy.status",
        "short" : "active | administratively-completed | approved | closed-to-accrual | closed-to-accrual-and-intervention | completed | disapproved | in-review | temporarily-closed-to-accrual | temporarily-closed-to-accrual-and-intervention | withdrawn",
        "definition" : "The current state of the study.",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.status",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "code"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "This element is labeled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid",
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyStatus"
            }
          ],
          "strength" : "required",
          "description" : "Codes that convey the current status of the research study.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-status|4.0.0"
        },
        "mapping" : [
          {
            "identity" : "w5",
            "map" : "FiveWs.status"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyOverallStatus.code"
          },
          {
            "identity" : "rim",
            "map" : ".status"
          }
        ]
      },
      {
        "id" : "ResearchStudy.primaryPurposeType",
        "path" : "ResearchStudy.primaryPurposeType",
        "short" : "treatment | prevention | diagnostic | supportive-care | screening | health-services-research | basic-science | device-feasibility",
        "definition" : "The type of study based upon the intent of the study's activities. A classification of the intent of the study.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.primaryPurposeType",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyPrimaryPurposeType"
            }
          ],
          "strength" : "extensible",
          "description" : "Codes for the main intent of the study.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-prim-purp-type"
        },
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolVersion.primaryPurposeTypeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.phase",
        "path" : "ResearchStudy.phase",
        "short" : "n-a | early-phase-1 | phase-1 | phase-1-phase-2 | phase-2 | phase-2-phase-3 | phase-3 | phase-4",
        "definition" : "The stage in the progression of a therapy from initial experimental use in humans in clinical trials to post-market evaluation.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.phase",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyPhase"
            }
          ],
          "strength" : "example",
          "description" : "Codes for the stage in the progression of a therapy from initial experimental use in humans in clinical trials to post-market evaluation.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-phase"
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Study Phase"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolVersion.phaseCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.category",
        "path" : "ResearchStudy.category",
        "short" : "Classifications for the study",
        "definition" : "Codes categorizing the type of study such as investigational vs. observational, type of blinding, type of randomization, safety vs. efficacy, etc.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.category",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyCategory"
            }
          ],
          "strength" : "example",
          "description" : "Codes that describe the type of research study. E.g. Study phase, Interventional/Observational, blinding type, etc."
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Study Type; Primary Purpose; Interventional Model; Masking; Allocation; study Classification; Observational Study Model; Time Perspective; Biospecimen Retention"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "InterventionalStudyProtocolVersion; InterventionalStudyProtocol.allocationCode; InterventionalStudyProtocol.blindedRoleCode; InterventionalStudyProtocol.blindingSchemaCode; InterventionalStudyProtocol.controlTypeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.focus",
        "path" : "ResearchStudy.focus",
        "short" : "Drugs, devices, etc. under study",
        "definition" : "The medication(s), food(s), therapy(ies), device(s) or other concerns or interventions that the study is seeking to gain more information about.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.focus",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyFocus"
            }
          ],
          "strength" : "example",
          "description" : "Codes for medications, devices and other interventions."
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Focus of Study"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.what[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "InterventionalStudyProtocol.interventionTypeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.condition",
        "path" : "ResearchStudy.condition",
        "short" : "Condition being studied",
        "definition" : "The condition that is the focus of the study. For example, In a study to examine risk factors for Lupus, might have as an inclusion criterion \"healthy volunteer\", but the target condition code would be a Lupus SNOMED code.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.condition",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ConditionCode"
            }
          ],
          "strength" : "example",
          "description" : "Identification of the condition or diagnosis.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/condition-code"
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Conditions"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.what[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyCondition.code"
          }
        ]
      },
      {
        "id" : "ResearchStudy.contact",
        "path" : "ResearchStudy.contact",
        "short" : "Contact details for the study",
        "definition" : "Contact details to assist a user in learning more about or engaging with the study.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.contact",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "ContactDetail"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Central Contact; Central Contact Backup; Overall Study Officials; Facility Contact & Backup (if Study tied to only one location); Investigators"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "PointOfContact > Project > Research Project > Study > StudyProtocol > StudyProtocolVersion"
          }
        ]
      },
      {
        "id" : "ResearchStudy.relatedArtifact",
        "path" : "ResearchStudy.relatedArtifact",
        "short" : "References and dependencies",
        "definition" : "Citations, references and other related documents.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.relatedArtifact",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "RelatedArtifact"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Citations, Links, Available Study Data/Documents"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolDocument, StudyProtocolDocumentVersion"
          }
        ]
      },
      {
        "id" : "ResearchStudy.keyword",
        "path" : "ResearchStudy.keyword",
        "short" : "Used to search for the study",
        "definition" : "Key terms to aid in searching for or filtering the study.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.keyword",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyKeyword"
            }
          ],
          "strength" : "example",
          "description" : "Words associated with the study that may be useful in discovery."
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Keywords"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "DocumentVersion.keywordCode; DocumentVersion.keywordText"
          }
        ]
      },
      {
        "id" : "ResearchStudy.location",
        "path" : "ResearchStudy.location",
        "short" : "Geographic region(s) for study",
        "definition" : "Indicates a country, state or other region where the study is taking place.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.location",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "Jurisdiction"
            },
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean" : true
            }
          ],
          "strength" : "extensible",
          "description" : "Countries and regions within which this artifact is targeted for use.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/jurisdiction"
        },
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolVersion.participatingLocationCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.description",
        "path" : "ResearchStudy.description",
        "short" : "What this is study doing",
        "definition" : "A full description of how the study is being conducted.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.description",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "markdown"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Detailed Description"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolDocumentVersion.publicDescription"
          }
        ]
      },
      {
        "id" : "ResearchStudy.enrollment",
        "path" : "ResearchStudy.enrollment",
        "short" : "Inclusion & exclusion criteria",
        "definition" : "Reference to a Group that defines the criteria for and quantity of subjects participating in the study. E.g. \" 200 female Europeans between the ages of 20 and 45 with early onset diabetes\".",
        "comment" : "The Group referenced should not generally enumerate specific subjects. Subjects will be linked to the study using the ResearchSubject resource.",
        "alias" : [
          "patient"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.enrollment",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Group"
            ]
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Enrollment; Number of Groups/Cohorts (= number of \"enrollment\" instances); Groups (Group/Cohort Label = Group.name; Group/Cohort Description = Group.description); Eligibility (Group criteria)"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.subject[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "InterventionalStudyProtocol.interventionGroupQuantity"
          },
          {
            "identity" : "rim",
            "map" : ".participation[typeCode=SBJ].role"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.subject"
          }
        ]
      },
      {
        "id" : "ResearchStudy.period",
        "path" : "ResearchStudy.period",
        "short" : "When the study began and ended",
        "definition" : "Identifies the start date and the expected (or actual, depending on status) end date for the study.",
        "alias" : [
          "timing"
        ],
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.period",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "Period"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Study Start Date (start); Study Completion Date (end)"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.done[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "ProjectConduct.dateRange; StudyProtocolVersion.plannedDuration"
          },
          {
            "identity" : "rim",
            "map" : ".effectiveTime"
          }
        ]
      },
      {
        "id" : "ResearchStudy.sponsor",
        "path" : "ResearchStudy.sponsor",
        "short" : "Organization that initiates and is legally responsible for the study",
        "definition" : "An organization that initiates the investigation and is legally responsible for the study.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.sponsor",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Organization"
            ]
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Sponsor"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.actor"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "RegulatoryApplicationSponsor; StudyLegalSponsor; StudyProtocolVersion.responsiblePartyCode"
          },
          {
            "identity" : "rim",
            "map" : ".participation[typeCode=PRF].role[scoper.determinerCode=INSTANCE]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.principalInvestigator",
        "path" : "ResearchStudy.principalInvestigator",
        "short" : "Researcher who oversees multiple aspects of the study",
        "definition" : "A researcher in a study who oversees multiple aspects of the study, such as concept development, protocol writing, protocol submission for IRB approval, participant recruitment, informed consent, data collection, analysis, interpretation and presentation.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.principalInvestigator",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Practitioner",
              "http://hl7.org/fhir/StructureDefinition/PractitionerRole"
            ]
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Principal Investigator"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.actor"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyInvestigator"
          }
        ]
      },
      {
        "id" : "ResearchStudy.site",
        "path" : "ResearchStudy.site",
        "short" : "Facility where study activities are conducted",
        "definition" : "A facility in which study activities are conducted.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.site",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Location"
            ]
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Facility"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.where[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "PlannedStudySite; StudySite"
          }
        ]
      },
      {
        "id" : "ResearchStudy.reasonStopped",
        "path" : "ResearchStudy.reasonStopped",
        "short" : "accrual-goal-met | closed-due-to-toxicity | closed-due-to-lack-of-study-progress | temporarily-closed-per-study-design",
        "definition" : "A description and/or code explaining the premature termination of the study.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.reasonStopped",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyReasonStopped"
            }
          ],
          "strength" : "example",
          "description" : "Codes for why the study ended prematurely.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-reason-stopped"
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Why Study Stopped"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.why[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyOverallStatus.studyStoppedReasonCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.note",
        "path" : "ResearchStudy.note",
        "short" : "Comments made about the study",
        "definition" : "Comments made about the study by the performer, subject or other participants.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.note",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Annotation"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping"
          },
          {
            "identity" : "rim",
            "map" : ".inboundRelationship(typeCode=SUBJ].source[classCode=ANNGEN, moodCode=EVN].value[xsi:type=ST]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm",
        "path" : "ResearchStudy.arm",
        "short" : "Defined path through the study for a subject",
        "definition" : "Describes an expected sequence of events for one of the participants of a study. E.g. Exposure to drug A, wash-out, exposure to drug B, wash-out, follow-up.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.arm",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "Element"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arms"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.id",
        "path" : "ResearchStudy.arm.id",
        "representation" : [
          "xmlAttr"
        ],
        "short" : "Unique id for inter-element referencing",
        "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Element.id",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "string"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.extension",
        "path" : "ResearchStudy.arm.extension",
        "short" : "Additional content defined by implementations",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias" : [
          "extensions",
          "user content"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Element.extension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.modifierExtension",
        "path" : "ResearchStudy.arm.modifierExtension",
        "short" : "Extensions that cannot be ignored even if unrecognized",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias" : [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "BackboneElement.modifierExtension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.name",
        "path" : "ResearchStudy.arm.name",
        "short" : "Label for study arm",
        "definition" : "Unique, human-readable label for this arm of the study.",
        "min" : 1,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.arm.name",
          "min" : 1,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "string"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arm Label"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm.name"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.type",
        "path" : "ResearchStudy.arm.type",
        "short" : "Categorization of study arm",
        "definition" : "Categorization of study arm, e.g. experimental, active comparator, placebo comparater.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.arm.type",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arm Type"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm.typeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.description",
        "path" : "ResearchStudy.arm.description",
        "short" : "Short explanation of study path",
        "definition" : "A succinct description of the path through the study that would be followed by a subject adhering to this arm.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.arm.description",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "string"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arm Description"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm.description"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective",
        "path" : "ResearchStudy.objective",
        "short" : "A goal for the study",
        "definition" : "A goal that the study is aiming to achieve in terms of a scientific question to be answered by the analysis of data collected during the study.",
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "ResearchStudy.objective",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ],
        "constraint" : [
          {
            "key" : "ele-1",
            "severity" : "error",
            "human" : "All FHIR elements must have a @value or children",
            "expression" : "hasValue() or (children().count() > id.count())",
            "xpath" : "@value|f:*|h:div",
            "source" : "Element"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyObjective"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective.id",
        "path" : "ResearchStudy.objective.id",
        "representation" : [
          "xmlAttr"
        ],
        "short" : "Unique id for inter-element referencing",
        "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "Element.id",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "string"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective.extension",
        "path" : "ResearchStudy.objective.extension",
        "short" : "Additional content defined by implementations",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "alias" : [
          "extensions",
          "user content"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "Element.extension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "n/a"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective.modifierExtension",
        "path" : "ResearchStudy.objective.modifierExtension",
        "short" : "Extensions that cannot be ignored even if unrecognized",
        "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
        "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
        "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
        "alias" : [
          "extensions",
          "user content",
          "modifiers"
        ],
        "min" : 0,
        "max" : "*",
        "base" : {
          "path" : "BackboneElement.modifierExtension",
          "min" : 0,
          "max" : "*"
        },
        "type" : [
          {
            "code" : "Extension"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "rim",
            "map" : "N/A"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective.name",
        "path" : "ResearchStudy.objective.name",
        "short" : "Label for the objective",
        "definition" : "Unique, human-readable label for this objective of the study.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.objective.name",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "string"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping (BRIDG has a description, but not a name)"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective.type",
        "path" : "ResearchStudy.objective.type",
        "short" : "primary | secondary | exploratory",
        "definition" : "The kind of study objective.",
        "min" : 0,
        "max" : "1",
        "base" : {
          "path" : "ResearchStudy.objective.type",
          "min" : 0,
          "max" : "1"
        },
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isModifier" : false,
        "isSummary" : false,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyObjectiveType"
            }
          ],
          "strength" : "preferred",
          "description" : "Codes for the kind of study objective.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-objective-type"
        },
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyObjective.typeCode"
          }
        ]
      }
    ]
  },
  "differential" : {
    "element" : [
      {
        "id" : "ResearchStudy",
        "path" : "ResearchStudy",
        "short" : "Investigation to increase healthcare-related patient-independent knowledge",
        "definition" : "A process where a researcher or organization plans and then executes a series of steps intended to increase the field of healthcare-related knowledge. This includes studies of safety, efficacy, comparative effectiveness and other information about medications, devices, therapies and other interventional and investigative techniques. A ResearchStudy involves the gathering of information about human or animal subjects.",
        "comment" : "Need to make sure we encompass public health studies.",
        "alias" : [
          "Clinical Trial",
          "Study"
        ],
        "min" : 0,
        "max" : "*",
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "ObservationalStudyProtocolVersion; Study;\nStudyProtocolVersion"
          },
          {
            "identity" : "v2",
            "map" : "OBX"
          },
          {
            "identity" : "rim",
            "map" : "Observation[classCode=CLNTRL, moodCode=EVN]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.identifier",
        "path" : "ResearchStudy.identifier",
        "short" : "Business Identifier for study",
        "definition" : "Identifiers assigned to this research study by the sponsor or other systems.",
        "requirements" : "Allows identification of the research study as it is known by various participating systems and in a way that remains consistent across servers.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "Identifier"
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Organization's Unique Protocol ID; Secondary IDs"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.identifier"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping (although there is DocumentVersion.identifier > StudyProtocolDocumentVersion, this is arguably a different semantic)"
          },
          {
            "identity" : "rim",
            "map" : ".identifier"
          }
        ]
      },
      {
        "id" : "ResearchStudy.title",
        "path" : "ResearchStudy.title",
        "short" : "Name for this study",
        "definition" : "A short, descriptive user-friendly label for the study.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "string"
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Brief Title"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping (although there is StudyProtocolDocumentVersionPublicTitle this is arguably a different semantic: title of a document vs title of a research study)"
          }
        ]
      },
      {
        "id" : "ResearchStudy.protocol",
        "path" : "ResearchStudy.protocol",
        "short" : "Steps followed in executing study",
        "definition" : "The set of steps expected to be performed as part of the execution of the study.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/PlanDefinition"
            ]
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Interventions; Arm/Intervention Cross-Reference"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolDocumentVersionPublicTitle.name"
          },
          {
            "identity" : "rim",
            "map" : ".outboundRelationship[typeCode=DEFN].target"
          }
        ]
      },
      {
        "id" : "ResearchStudy.partOf",
        "path" : "ResearchStudy.partOf",
        "short" : "Part of larger study",
        "definition" : "A larger research study of which this particular study is a component or step.",
        "requirements" : "Allows breaking a study into components (e.g. by study site) each with their own PI, status, enrollment, etc.",
        "alias" : [
          "container"
        ],
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/ResearchStudy"
            ]
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "CompanionStudyRelationship"
          },
          {
            "identity" : "rim",
            "map" : ".inboundRelationship[typeCode=COMP].source[moodCode=EVN]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.status",
        "path" : "ResearchStudy.status",
        "short" : "active | administratively-completed | approved | closed-to-accrual | closed-to-accrual-and-intervention | completed | disapproved | in-review | temporarily-closed-to-accrual | temporarily-closed-to-accrual-and-intervention | withdrawn",
        "definition" : "The current state of the study.",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "code"
          }
        ],
        "isModifier" : true,
        "isModifierReason" : "This element is labeled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid",
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyStatus"
            }
          ],
          "strength" : "required",
          "description" : "Codes that convey the current status of the research study.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-status|4.0.0"
        },
        "mapping" : [
          {
            "identity" : "w5",
            "map" : "FiveWs.status"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyOverallStatus.code"
          },
          {
            "identity" : "rim",
            "map" : ".status"
          }
        ]
      },
      {
        "id" : "ResearchStudy.primaryPurposeType",
        "path" : "ResearchStudy.primaryPurposeType",
        "short" : "treatment | prevention | diagnostic | supportive-care | screening | health-services-research | basic-science | device-feasibility",
        "definition" : "The type of study based upon the intent of the study's activities. A classification of the intent of the study.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyPrimaryPurposeType"
            }
          ],
          "strength" : "extensible",
          "description" : "Codes for the main intent of the study.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-prim-purp-type"
        },
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolVersion.primaryPurposeTypeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.phase",
        "path" : "ResearchStudy.phase",
        "short" : "n-a | early-phase-1 | phase-1 | phase-1-phase-2 | phase-2 | phase-2-phase-3 | phase-3 | phase-4",
        "definition" : "The stage in the progression of a therapy from initial experimental use in humans in clinical trials to post-market evaluation.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyPhase"
            }
          ],
          "strength" : "example",
          "description" : "Codes for the stage in the progression of a therapy from initial experimental use in humans in clinical trials to post-market evaluation.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-phase"
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Study Phase"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolVersion.phaseCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.category",
        "path" : "ResearchStudy.category",
        "short" : "Classifications for the study",
        "definition" : "Codes categorizing the type of study such as investigational vs. observational, type of blinding, type of randomization, safety vs. efficacy, etc.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyCategory"
            }
          ],
          "strength" : "example",
          "description" : "Codes that describe the type of research study. E.g. Study phase, Interventional/Observational, blinding type, etc."
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Study Type; Primary Purpose; Interventional Model; Masking; Allocation; study Classification; Observational Study Model; Time Perspective; Biospecimen Retention"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "InterventionalStudyProtocolVersion; InterventionalStudyProtocol.allocationCode; InterventionalStudyProtocol.blindedRoleCode; InterventionalStudyProtocol.blindingSchemaCode; InterventionalStudyProtocol.controlTypeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.focus",
        "path" : "ResearchStudy.focus",
        "short" : "Drugs, devices, etc. under study",
        "definition" : "The medication(s), food(s), therapy(ies), device(s) or other concerns or interventions that the study is seeking to gain more information about.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyFocus"
            }
          ],
          "strength" : "example",
          "description" : "Codes for medications, devices and other interventions."
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Focus of Study"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.what[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "InterventionalStudyProtocol.interventionTypeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.condition",
        "path" : "ResearchStudy.condition",
        "short" : "Condition being studied",
        "definition" : "The condition that is the focus of the study. For example, In a study to examine risk factors for Lupus, might have as an inclusion criterion \"healthy volunteer\", but the target condition code would be a Lupus SNOMED code.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ConditionCode"
            }
          ],
          "strength" : "example",
          "description" : "Identification of the condition or diagnosis.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/condition-code"
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Conditions"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.what[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyCondition.code"
          }
        ]
      },
      {
        "id" : "ResearchStudy.contact",
        "path" : "ResearchStudy.contact",
        "short" : "Contact details for the study",
        "definition" : "Contact details to assist a user in learning more about or engaging with the study.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "ContactDetail"
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Central Contact; Central Contact Backup; Overall Study Officials; Facility Contact & Backup (if Study tied to only one location); Investigators"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "PointOfContact > Project > Research Project > Study > StudyProtocol > StudyProtocolVersion"
          }
        ]
      },
      {
        "id" : "ResearchStudy.relatedArtifact",
        "path" : "ResearchStudy.relatedArtifact",
        "short" : "References and dependencies",
        "definition" : "Citations, references and other related documents.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "RelatedArtifact"
          }
        ],
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Citations, Links, Available Study Data/Documents"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolDocument, StudyProtocolDocumentVersion"
          }
        ]
      },
      {
        "id" : "ResearchStudy.keyword",
        "path" : "ResearchStudy.keyword",
        "short" : "Used to search for the study",
        "definition" : "Key terms to aid in searching for or filtering the study.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyKeyword"
            }
          ],
          "strength" : "example",
          "description" : "Words associated with the study that may be useful in discovery."
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Keywords"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "DocumentVersion.keywordCode; DocumentVersion.keywordText"
          }
        ]
      },
      {
        "id" : "ResearchStudy.location",
        "path" : "ResearchStudy.location",
        "short" : "Geographic region(s) for study",
        "definition" : "Indicates a country, state or other region where the study is taking place.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "Jurisdiction"
            },
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
              "valueBoolean" : true
            }
          ],
          "strength" : "extensible",
          "description" : "Countries and regions within which this artifact is targeted for use.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/jurisdiction"
        },
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolVersion.participatingLocationCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.description",
        "path" : "ResearchStudy.description",
        "short" : "What this is study doing",
        "definition" : "A full description of how the study is being conducted.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "markdown"
          }
        ],
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Detailed Description"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyProtocolDocumentVersion.publicDescription"
          }
        ]
      },
      {
        "id" : "ResearchStudy.enrollment",
        "path" : "ResearchStudy.enrollment",
        "short" : "Inclusion & exclusion criteria",
        "definition" : "Reference to a Group that defines the criteria for and quantity of subjects participating in the study. E.g. \" 200 female Europeans between the ages of 20 and 45 with early onset diabetes\".",
        "comment" : "The Group referenced should not generally enumerate specific subjects. Subjects will be linked to the study using the ResearchSubject resource.",
        "alias" : [
          "patient"
        ],
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Group"
            ]
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Enrollment; Number of Groups/Cohorts (= number of \"enrollment\" instances); Groups (Group/Cohort Label = Group.name; Group/Cohort Description = Group.description); Eligibility (Group criteria)"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.subject[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "InterventionalStudyProtocol.interventionGroupQuantity"
          },
          {
            "identity" : "rim",
            "map" : ".participation[typeCode=SBJ].role"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.subject"
          }
        ]
      },
      {
        "id" : "ResearchStudy.period",
        "path" : "ResearchStudy.period",
        "short" : "When the study began and ended",
        "definition" : "Identifies the start date and the expected (or actual, depending on status) end date for the study.",
        "alias" : [
          "timing"
        ],
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "Period"
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Study Start Date (start); Study Completion Date (end)"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.done[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "ProjectConduct.dateRange; StudyProtocolVersion.plannedDuration"
          },
          {
            "identity" : "rim",
            "map" : ".effectiveTime"
          }
        ]
      },
      {
        "id" : "ResearchStudy.sponsor",
        "path" : "ResearchStudy.sponsor",
        "short" : "Organization that initiates and is legally responsible for the study",
        "definition" : "An organization that initiates the investigation and is legally responsible for the study.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Organization"
            ]
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Sponsor"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.actor"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "RegulatoryApplicationSponsor; StudyLegalSponsor; StudyProtocolVersion.responsiblePartyCode"
          },
          {
            "identity" : "rim",
            "map" : ".participation[typeCode=PRF].role[scoper.determinerCode=INSTANCE]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.principalInvestigator",
        "path" : "ResearchStudy.principalInvestigator",
        "short" : "Researcher who oversees multiple aspects of the study",
        "definition" : "A researcher in a study who oversees multiple aspects of the study, such as concept development, protocol writing, protocol submission for IRB approval, participant recruitment, informed consent, data collection, analysis, interpretation and presentation.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Practitioner",
              "http://hl7.org/fhir/StructureDefinition/PractitionerRole"
            ]
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Principal Investigator"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.actor"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyInvestigator"
          }
        ]
      },
      {
        "id" : "ResearchStudy.site",
        "path" : "ResearchStudy.site",
        "short" : "Facility where study activities are conducted",
        "definition" : "A facility in which study activities are conducted.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "Reference",
            "targetProfile" : [
              "http://hl7.org/fhir/StructureDefinition/Location"
            ]
          }
        ],
        "isSummary" : true,
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Facility"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.where[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "PlannedStudySite; StudySite"
          }
        ]
      },
      {
        "id" : "ResearchStudy.reasonStopped",
        "path" : "ResearchStudy.reasonStopped",
        "short" : "accrual-goal-met | closed-due-to-toxicity | closed-due-to-lack-of-study-progress | temporarily-closed-per-study-design",
        "definition" : "A description and/or code explaining the premature termination of the study.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "isSummary" : true,
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyReasonStopped"
            }
          ],
          "strength" : "example",
          "description" : "Codes for why the study ended prematurely.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-reason-stopped"
        },
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Why Study Stopped"
          },
          {
            "identity" : "w5",
            "map" : "FiveWs.why[x]"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyOverallStatus.studyStoppedReasonCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.note",
        "path" : "ResearchStudy.note",
        "short" : "Comments made about the study",
        "definition" : "Comments made about the study by the performer, subject or other participants.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "Annotation"
          }
        ],
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping"
          },
          {
            "identity" : "rim",
            "map" : ".inboundRelationship(typeCode=SUBJ].source[classCode=ANNGEN, moodCode=EVN].value[xsi:type=ST]"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm",
        "path" : "ResearchStudy.arm",
        "short" : "Defined path through the study for a subject",
        "definition" : "Describes an expected sequence of events for one of the participants of a study. E.g. Exposure to drug A, wash-out, exposure to drug B, wash-out, follow-up.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ],
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arms"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.name",
        "path" : "ResearchStudy.arm.name",
        "short" : "Label for study arm",
        "definition" : "Unique, human-readable label for this arm of the study.",
        "min" : 1,
        "max" : "1",
        "type" : [
          {
            "code" : "string"
          }
        ],
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arm Label"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm.name"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.type",
        "path" : "ResearchStudy.arm.type",
        "short" : "Categorization of study arm",
        "definition" : "Categorization of study arm, e.g. experimental, active comparator, placebo comparater.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arm Type"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm.typeCode"
          }
        ]
      },
      {
        "id" : "ResearchStudy.arm.description",
        "path" : "ResearchStudy.arm.description",
        "short" : "Short explanation of study path",
        "definition" : "A succinct description of the path through the study that would be followed by a subject adhering to this arm.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "string"
          }
        ],
        "mapping" : [
          {
            "identity" : "clinicaltrials-gov",
            "map" : "Arm Description"
          },
          {
            "identity" : "BRIDG5.1",
            "map" : "Arm.description"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective",
        "path" : "ResearchStudy.objective",
        "short" : "A goal for the study",
        "definition" : "A goal that the study is aiming to achieve in terms of a scientific question to be answered by the analysis of data collected during the study.",
        "min" : 0,
        "max" : "*",
        "type" : [
          {
            "code" : "BackboneElement"
          }
        ],
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyObjective"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective.name",
        "path" : "ResearchStudy.objective.name",
        "short" : "Label for the objective",
        "definition" : "Unique, human-readable label for this objective of the study.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "string"
          }
        ],
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "No BRIDG mapping (BRIDG has a description, but not a name)"
          }
        ]
      },
      {
        "id" : "ResearchStudy.objective.type",
        "path" : "ResearchStudy.objective.type",
        "short" : "primary | secondary | exploratory",
        "definition" : "The kind of study objective.",
        "min" : 0,
        "max" : "1",
        "type" : [
          {
            "code" : "CodeableConcept"
          }
        ],
        "binding" : {
          "extension" : [
            {
              "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
              "valueString" : "ResearchStudyObjectiveType"
            }
          ],
          "strength" : "preferred",
          "description" : "Codes for the kind of study objective.",
          "valueSet" : "http://hl7.org/fhir/ValueSet/research-study-objective-type"
        },
        "mapping" : [
          {
            "identity" : "BRIDG5.1",
            "map" : "StudyObjective.typeCode"
          }
        ]
      }
    ]
  }
}